Abstract
Objective To observe the effect and complications of vitrectomy combined with intraocular silicon oil or C3F8 filling for proliferative diabetic retinopathy (PDR).Methods Eighty-six consecutive patients (101 eyes) with PDR-related vitreous hemorrhage who underwent primary standard three-port vitrectomy and intraocular tamponade of silicone oil or C3 F8 were included in this retrospective study.They were divided into silicone oil group and C3F8 groups.There was no statistically significant difference between these two groups of patients for gender,age,duration of diabetes,fasting glucose,history of hypertension,diabetic kidney disease history,history of cardiac and vascular diseases,body mass index and smoking history.There was statistically significant difference between these two groups of patients for visual acuity (Z=-2.604,P=0.009).There was no statistically significant difference between these two groups of patients for intraocular pressure before surgery (Z=0.064,P=0.949).The mean follow-up was (20.3±16.4) months with a range from 1 to 47 months.The patients were followed up for visual acuity,intraocular pressure,neovascular glaucoma (NVG),the incidence of retinal detachment,recurrent vitreous hemorrhage,and repeated operation for complications.Results Visual acuity (t=-3.932,-8.326; P=0.000,0.000) and intraocular pressure (t=-3.159,-2.703; P=0.006,0.009) were changed significantly after surgery for both groups.Between these two groups after surgery,there were significant differences of visual acuity (Z=-1.879,P=0.040),intraocular pressure (Z=-3.593,P=0.000),and complications (revision operation,retinal detachment,recurrent vitreous hemorrhage and NVG) (t =-2.777,-2.102,-2.308,-2.013 ; P ＜ 0.05).Conclusion Intraocular silicone oil tamponade can reduce the postoperative complications of PDR,especially for severe retinal neovascularization,exudation associated with retinal edema. Key words: Diabetic retinopathy/complications; Vitreous hemorrhage/surgery; Vitrectomy; Silicone oils/therapeutic use; Noble gases/therapeutic use
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
