Abstract

The gut microbiota in mice consumes glycine, one of three amino acids needed by host animals to make the powerful antioxidant peptide glutathione, according to Adil Mardinoglu at the Royal Institute of Technology in Stockholm and Chalmers University of Technology, Gothenburg, both in Sweden, and his collaborators in Sweden and Denmark. He calls this example of the gut microbiota exerting partial control over this host metabolic pathway “surprising,” and suggests that “imbalances in the composition of bacteria [within the microbiota] may lead to the progression of chronic diseases.” Details appeared 16 October 2015 in Molecular Systems Biology (doi:10.15252/msb.20156487).

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