Bundled Bone Grafting Effectively Promotes Callus Growth and Accelerates Fracture Healing in the Operation of Nonunion or Bone Defects

Abstract

This study aims to investigate the clinical application potential of bundled bone grafting in the management of nonunion or bone defects after internal fixation. A total of 34 patients with nonunion or partial bone defects after internal fixation of femoral shaft fracture at our hospital from March 2018 to January 2020 were included in this study. They were randomly divided into a control group treated with filling/compressed bone grafting (n = 17) and a test group receiving bundled bone grafting (n = 17) patients receiving bundled bone grafting. The healing rate of fracture, the length and healing time of callus growth, and the lower extremity function were assessed in the two groups. The test group exhibited a significantly higher fracture healing rate compared to the control group (100% vs. 76.47%, P < 0.05). Moreover, the test group demonstrated superior callus growth length when compared to the control group [(2.64±0.48) cm vs. (1.72 ±0.35) cm, P < 0.05]. Additionally, the test group exhibited a significantly shorter healing time than the control group [(6.73 ± 1.24) months vs. (8.12 ± 1.48) months, P < 0.05]. The total efficacy rate for lower extremity function in the test group was significantly higher at 94.12% compared to the control group’s rate of 64.71%. In conclusion, the utilization of bundled bone grafting can promote callus growth and accelerate fracture healing in the management of nonunion or bone defects after internal fixation.