Abstract
Building a Sea Urchin on Shifting Sands
Highlights
Constructing a multicellular organism from scratch is a staggeringly challenging task
The development of multicellular organisms is stuck on the horns of a tricky dilemma
Long-term survival of a species in the face of changing environmental conditions requires that such an organism is able to change, in a genetically determined way, to provide the variability on which natural selection can act
Summary
Constructing a multicellular organism from scratch is a staggeringly challenging task. Long-term survival of a species in the face of changing environmental conditions requires that such an organism is able to change, in a genetically determined way, to provide the variability on which natural selection can act. Sea urchin embryos develop from single cells to free-swimming larvae over 4 days, and the authors set out to examine how the struggle between robustness and evolvability plays out over this timescale.
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