Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease pandemic (otherwise known as COVID-19) was first reported on 31 December 2019 by the China World Health Organization country office following a cluster of pneumonia cases in Wuhan City, Hubei Province, China. SARS-CoV-2 has since been confirmed as the causative agent of COVID-19. From March through May 2020, paediatricians in the UK and elsewhere noted hospitalisations of children who developed fever and multisystem inflammation. Some of these children were critically ill with shock and multiorgan failure and required intensive care, while some had characteristics that were similar to Kawasaki disease (KD) or KD shock syndrome. The clinical evidence suggested the emergence of a paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS).

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