Bridge-Mediated RET between Two Chiral Molecules

Abstract

Molecular quantum electrodynamics (QED) theory is employed to calculate the rate of resonance energy transfer (RET) between a donor, D, described by an electric dipole and quadrupole, and magnetic dipole coupling, and an identical acceptor molecule, A, that is mediated by a third body, T, which is otherwise inert. A single virtual photon propagates between D and T, and between T and A. Time-dependent perturbation theory is used to compute the matrix element, from which the transfer rate is evaluated using the Fermi golden rule. This extends previous studies that were limited to the electric dipole approximation only and admits the possibility of the exchange of excitation between a chiral emitter and absorber. Rate terms are computed for specific pure and mixed multipole-dependent contributions of D and A for both an oriented arrangement of the three particles and for the freely tumbling situation. Mixed multipole moment contributions, such as those involving electric–magnetic dipole or electric dipole–quadrupole coupling at one center, do not survive random orientational averaging. Interestingly, the mixed electric–magnetic dipole D and A rate term is non-vanishing and discriminatory, exhibiting a dependence on the chirality of the emitter and absorber, and is entirely retarded. It vanishes, however, if D and A are oriented perpendicularly to one another. Near- and far-zone asymptotes of isotropic contributions to the rate are also evaluated, demonstrating radiationless short-range transfer and inverse-square radiative exchange at very large separations.