Abstract
Nuclear chromatin is a dynamic structure made of arrays of nucleosomes with different sizes and degrees of compaction. Structural rearrangements in chromatin rely on inter and intra nucleosome dynamics and are essential for gene regulation and cell fate transitions. Understanding these rearrangements requires elucidating nucleosome structural flexibility and how different factors affect it. In the nucleosome, 145-147 base pairs of DNA are wrapped around an octamer formed by four histone proteins.
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