Abstract
A 60-year-old woman was admitted with abdominal distension. Ten years prior, she had been treated for breast cancer (lobular carcinoma; pT1c, G2, pN1 bi, pM0; estrogen and progesterone receptor-positive, Her2neu negative) by breast-preserving surgery and adjuvant radiochemotherapy. The follow-up had been uneventful until 6 months prior to admission, when an increase in tumor marker Ca 15-3 had been detected. An extensive work-up during the preceding 6 months had failed to detect metastatic disease or a secondary breast cancer. The work-up after admission, including laparoscopy, revealed ascites due to peritoneal metastatic disease. On endoscopic examination of the greater curve of the stomach, 7 superficial type IIa polypoid lesions 1 Update on the Paris classification of superficial neoplastic lesions in the digestive tract. Endoscopy. 2005; 37: 570-578 Crossref PubMed Scopus (570) Google Scholar with a maximum diameter of 3 mm were detected (Fig. 1). Histologically, these lesions were identified as infiltration of breast cancer cells (Fig. 2) with a strong expression of estrogen receptors (Fig. 3). The patient was referred for palliative treatment with anti-estrogens and doxetacel, which resulted in a regression of ascites formation. Figure 2The lesions were histologically identified as infiltration of breast cancer cells (H&E, orig. mag. ×200). View Large Image Figure Viewer Download Hi-res image Figure 3The lession showed a strong expression of estrogen receptors (immunohistochemistry, orig. mag. ×200). View Large Image Figure Viewer Download Hi-res image
Published Version
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