Breast cancer associated with pregnancy

Abstract

Introduction. The problem of breast cancer associated with pregnancy for a long time attracts close attention. The incidence is relatively increasing, thanks in part to improved detection methods, but also to the growing trend towards late childbearing.Material and methods. The features of breast cancer treatment during pregnancy were studied, and the effect of pregnancy on the long-term prognosis and clinical course of breast cancer was evaluated.Results. All patients received treatment according to the clinical recommendations. Chemotherapeutic treatment was performed in 44 (77%) patients, surgical treatment in 54 (96%) cases, radiation therapy in 40(72%) patients, and hormone therapy in 24 (42%) women. Among the newborns, there were no significant malformations, one child (a girl) had an underdevelopment of the left lung tissue, and laterphysical development in accordance with age.Conclusion. The decision on the special treatment of breast cancer associated with pregnancy is made individually, the treatment has been planned together with obstetricians and gynecologists. Surgical and chemotherapeutic treatment (starting at 13 weeks) can be performed during pregnancy. Radiation therapy, hormone therapy, and targeted therapy should be postponed until delivery. Most patients have common forms of the disease and aggressive biological types of tumors. Currently, the features of the course of the disease, the prognosis, and the features of treatment in this category of patients are being studied.