Abstract

Brain Imaging Abnormalities in Autism Disorders

Highlights

  • Autism disorders are heterogeneous complex group of chronic disorders that have become increasingly known as pervasive developmental disorders since the 1980s

  • The aim of this paper is to report the association of brain imaging abnormalities in four autistic children

  • The first patient was a 41⁄2-year-old girl [Figure 1] who had atypical autism with mental retardation as evident by poor adaptive skill including lack of bowel control and poor spoon feeding with spilling when eating with spoon

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Summary

Introduction

Autism disorders are heterogeneous complex group of chronic disorders that have become increasingly known as pervasive developmental disorders since the 1980s. The autistic psychopathy reported in 1925 by Grunya Efimovna Sukhareva and Hans Asperger was similar, and it was called Lorna Wing “Asperger syndrome” in her 1981 publication of a series of case studies of children having the disorder.[3,6] Children having autism with poor language development and subnormal intelligence but without significant mental retardation are generally considered to have typical rather than the classical autism of Leo Kanner.[1,2,3,4,5] Children who have autism with significant mental retardation are generally considered to have atypical autism disorder Conclusion: Brain imaging abnormalities in patients with autism disorders include arachnoid cyst, agenesis of the corpus callosum, evidence of vasculitis (in Heller syndrome), and brain imaging abnormalities related to a coexisting condition such as cerebral palsy

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