Abstract
Both active surveillance (AS) and primary focal cryotherapy (PFC) are considered suitable approaches for men with low to intermediate risk prostate cancer (PCa). We aim to identify any differences in bowel, urinary, and sexual function that may exist between patients on AS and those who have undergone PFC.
Highlights
Prostate cancer (PCa) is the most common cause of cancer and the fifth most common cause of cancer death among men worldwide [1]
Data from the 179 remaining patients were reviewed for demographics, treatment method (AS vs. Primary focal cryotherapy (PFC)), prostate-specific antigen (PSA) levels at time of initial treatment, Gleason scores and grade groups, time to clinical follow-up, responses to both the Expanded Prostate Cancer Index Composite (EPIC) and the International Index of Erectile Function (IIEF) questionnaires, and use of phosphodiesterase-5 inhibitors, alpha blockers, and 5-α-reductase inhibitors
Neither anxiety about post-treatment PSA levels nor fear of recurrence of prostate cancer (PCa) were significantly different between the two groups (p = 0.494 and p = 0.551, respectively)
Summary
Prostate cancer (PCa) is the most common cause of cancer and the fifth most common cause of cancer death among men worldwide [1]. The D’Amico classification model stratifies men with PCa into groups with low, intermediate, or high risk of biochemical recurrence after treatment according to the patients’ clinical TNM stage, Gleason score, and pretreatment prostate-specific antigen (PSA) level [2]. While some authors have proposed changes to the D’Amico model, SCHOLSAcRhoSl.aDrlIyRPEaCgeTs. Open Access | Page 24 | The rapid decrease in temperature within the gland results in denaturation of proteins, disruption of blood supply, and apoptosis of cells upon thawing of the gland [14,15]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
