Abstract
Objectives To compare the different effects caused by different injection sites in bladder, in cases of female bladder pain syndrome/interstitial cystitis (BPS/IC) cured by botulinum toxin type A injection. Methods 60 cases were randomly divided into two groups. Cases of group A accepted botulinum toxin type A injection only on detrusor.Cases of group B accepted botulinum toxin type A injection on detrusor and trigone of urinary bladder.The following parameters were recorded to evaluate the effects after 8 weeks: average urination frequency, Maximum voiding, PUF scores and QOL scores. Results These parameters of two groups had no statistical differences before accepting treament. Efficacy in both groups obviously improved after treatment. Efficacy of group B improved more obviously than group A. Conclusions Botulinum toxintype A injection on bladder is a new effective method for female interstitial cystitis. Injection on detrusor and trigone of urinary bladder is better than injection only on detrusor. Key words: Cystitis, Interstitial; Pain; Syndrome; Botulinum Toxin Type A
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