Abstract
Objective. To define age-related dynamics of bone tissue mineralization in children, adolescents, and young people residing in Novosibirsk city. Material and Methods. A total of 1226 patients at the age of 6 to 23 years were examined. Bone mineral density (BMD) was evaluated by dual x-ray absorptiometry (DEXA) with bone densitometer and using pediatric software version and US sex and age reference database. Results. According to DEXA data the bone mineral accumulation in children spine tissue proceeds non-uniformly in different age periods. During the age period of 6 to 23 years the lumbar spine BMD increases by 0.525 g/cm2 (50.3 %) in males and by 0.454 g/cm2 (45.6 %) in females. In females a spine bone mineralization peak occurs at the age of 20–21, and in males – 22–23. Bone mineral density values directly correlate with sex and age parameters both in females and in males, and reliability of correlation ratios widely varies depending on the period of physiological development. Conclusion. The revealed patterns of spine bone mass accumulation in the growing children and adolescents should be accounted in diagnostics of osteopenia.
Highlights
To define age-related dynamics of bone tissue mineralization in children, adolescents, and young people residing in Novosibirsk city
During the age period of 6 to 23 years the lumbar spine Bone mineral density (BMD) increases by 0.525 g/cm2 (50.3 %) in males and by 0.454 g/cm2 (45.6 %) in females
Bone mineral density values directly correlate with sex and age parameters both in females and in males, and reliability of correlation ratios widely varies depending on the period of physiological development
Summary
Минеральная плотность костной ткани позвоночника у здорового населения детского, подросткового и юношеского возраста. Определение в зависимости от возраста динамики минерализации костной ткани позвоночника у практически здоровых жителей Новосибирска. Минеральная плотность костной ткани (МПКТ) оценивалась методом двухэнергетической рентгеновской абсорбциометрии с использованием остеоденситометра и с применением детских программ и американской нормативной половозрастной базы данных. В период от 6 до 23 лет МПКТ поясничного отдела позвоночника у представителей мужского пола увеличивается на 0,525 г/см (50,3 %), а женского – на 0,454 г/см (45,6 %). Пик минерализации костной ткани позвоночника у жителей Новосибирска в зависимости от пола и возраста разный: у девушек – 20–21 год, у юношей – 22–23 года. Выявленные закономерности накопления костной массы ткани позвоночника в процессе роста и развития детей и подростков необходимо учитывать при диагностике остеопенических состояний. Ключевые слова: минеральная плотность костной ткани, позвоночник, дети
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