Abstract
Objective: to define bone mineral density and bone turnover indicators in primary osteoarthrosis accompanied with osteodeficiency conditions of varying severity as a means of early osteoarthrosis detection in individuals. Review method. We analyzed 157 Russian and foreign studies of 2005-2022 retrieved from e-Library, Medline, PubMed, PubMed Central, Google Scholar, SpringerLink и Elsevier. The keyword search in Russian and English involved "primary osteoarthritis", "osteoporosis", "osteopenia", "bone mineral density", "markers of bone resorption", "bone formation markers", "bone metabolism regulators", "RANKL/RANK/OPG system". 35 studies were considered the most valuable and eventually reviewed. Conclusion. The analysis suggested that primary osteoarthrosis accompanied by osteodeficiency conditions can be assessed by determining bone mineral density, bone turnover indicators as well as bone turnover regulators.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have