Abstract
The aim of the present study was to evaluate bone loss at implants connected to abutments coated with a soda-lime glass containing silver nanoparticles, subjected to experimental peri-implantitis. Also the aging and erosion of the coating in mouth was studied. Five beagle dogs were used in the experiments. Three implants were placed in each mandible quadrant: in 2 of them, Glass/n-Ag coated abutments were connected to implant platform, 1 was covered with a Ti-mechanized abutment. Experimental peri-implantitis was induced in all implants after the submarginal placement of cotton ligatures, and three months after animals were euthanatized. Thickness and morphology of coating was studied in abutment cross-sections by SEM. Histology and histo-morphometric studies were carried on in undecalfied ground slides. After the induced peri-implantitis: 1.The abutment coating shown losing of thickness and cracking. 2. The histometry showed a significant less bone loss in the implants with glass/n-Ag coated abutments. A more symmetric cone of bone resorption was observed in the coated group. There were no significant differences in the peri-implantitis histological characteristics between both groups of implants. Within the limits of this in-vivo study, it could be affirmed that abutments coated with biocide soda-lime-glass-silver nanoparticles can reduce bone loss in experimental peri-implantitis. This achievement makes this coating a suggestive material to control peri-implantitis development and progression.
Highlights
Peri-implantitis has been cited as one of the key factors responsible for implant failure [1,2]
In this regards new implant designs have been commercialized seeking to reduce bone remodeling after osseointegration as well as modern implant abutment connection minimizing bacterial filtration- due to the impossibility of completely eliminating bacterial contamination, subgingival plaque formation is still a problem which often result in peri-implantitis; and ii) treatment based on mechanical debridation, antibiotic treatment and osseous regeneration when possible [6]
In the abutment coating loss may play a summation role the chemical micro-erosion caused by peri-implantitis, as it was already described in hydroxyapatite coatings [18]
Summary
Peri-implantitis has been cited as one of the key factors responsible for implant failure [1,2]. Some strategies have been developed in the peri-implantitis treatment in recent years [5]: i) prevention of bone loss around implants. The use of local antibiotics and antiplaque biocides, in addition to manual debridement seems to be an adequate treatment [7,8]. It seems that the eradication of resistance is impossible and development of resistance to any particular antibiotic is inevitable
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