Abstract
BackgroundPrognostic roles of BMI or diets for progression in CKD remain unclear.AimsWe prospectively investigated relationships between BMI and intake of energy/protein and risks of ESRD and mortality in a cohort of CKD patients with stage 3 or less in Taiwan. The median follow‐up time was 27.3 months.MethodsHigh dietary protein intake (DPI) was defined as ratio of intake/recommendation ≥110%; low dietary energy intake (DEI) was as the ratio <90%. High DPI and/or low DEI were classified as suboptimal intake.ResultsUpon adjusting for confounders, BMI 24 to 26.9 (RR=0.80), BMI≥27 (RR=0.70) had progressively lower (all p<0.05) risks of renal death or mortality than BMI<24, and suboptimal intake of either DPI or DEI (RR=1.86), suboptimal intake of both DEI and DPI (RR=2.51) showed significantly greater (all p<0.05) risks compared to the optimal counterpart based on Cox's proportional‐hazard models.ConclusionsBoth BMI and intake of energy and protein amount appear to associate with progression of CKD. Nutrition counseling may be needed for CKD patients with respect to optimal management of weight and diet.
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