Abstract
Several authors have demonstrated the feasibility and efficiency of Boron Neutron Capture Enhancement of Fast Neutron (BNCEFN) at their facility.1, 2, 3, 4, 5 The two major difficulties of this technique are to incorporate a large amount of 10B selectively into the tumor (>100µg/g) and to optimize neutron thermalization in the tissues. Unfortunately, it has been also demonstrated that the number of thermal neutrons per fast neutron Gy (nth.Gy−1) is inversely proportional to fast neutron energy, and strongly proportional to the size of fast neutron irradiation field.3, 4, 5 Thus, a dramatic decrease of thermal neutron flux is seen when the irradiation fields are reduced to conform the target volume.
Published Version
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