Abstract
Iron is an essential mineral for the human, animal and plant kingdom, being present in water, soil and air. In the organism, iron is found both as a ferrous ion (Fe2+) and as a ferric ion (Fe3+), being involved in oxidoreduction processes and as part of protein structure or in complexes with anions present in cells and tissues. The optimal iron concentration in the body depends on several characteristics (organism type, age, gender, environmental conditions - especially related to altitude, physiological status and others), but there is a rather small variation between the minimum and maximum required concentration -deficiency or excess having a detrimental effect on the organism. In the present work iron gluconate hydrate (10 mg Fe2+/kg body) has been administered intraperitoneally to rabbits, in two separate injections. We formulated a diet rich in plants with protective role, and at the end of the experiment the level of blood serum sodium, potassium, magnesium, ionic calcium, total calcium, iron and chlorine was measured. The results showed that iron overload led to a significant increase of potassium (55.74%), magnesium (31.57%), iron (20.86%) and calcium (with 19.69% total Ca and 17.19% ionic Ca), while the concentration of sodium and chlorine showed non-significant decreases (sodium decreased by 3.83%, and chlorine decreased by 1.58%). Therefore, the excess iron administered over a short period of time to rabbits influences the metabolism of several minerals such as potassium, magnesium, calcium, iron as well as sodium and chlorine and that is reflected in their blood serum level.
Highlights
Following Iron OverloadMIRELA AHMADI2, IOAN PET1*, LAVINIA STEF1, GABI DUMITRESCU1, SILVIA PATRUICA1, MARIOARA NICULA1, LILIANA PETCULESCU CIOCHINA1, MIHAELA POPA3, DOREL DRONCA1* 1Faculty of Veterinary Medicine, Banat’s University of Agricultural Sciences and Veterinary Medicine „King Michael I of Romania” from Timisoara - USAMVB, 119 Calea Aradului, 300645, Timisoara, Romania 2Faculty of Bioengineering of Animal Production, Banat’s University of Agricultural Sciences and Veterinary Medicine „King Michael I of Romania from Timisoara -USAMVB, 119 Calea Aradului, 300645, Timisoara, Romania 3Faculty of Engineering of Hunedoara, Polytechnic University of Timisoara
Iron is an essential mineral for the human, animal and plant kingdom, being present in water, soil and air
Our experiment showed that iron overload for a short period of time increases potassium, magnesium and calcium concentration in serum
Summary
MIRELA AHMADI2, IOAN PET1*, LAVINIA STEF1, GABI DUMITRESCU1, SILVIA PATRUICA1, MARIOARA NICULA1, LILIANA PETCULESCU CIOCHINA1, MIHAELA POPA3, DOREL DRONCA1* 1Faculty of Veterinary Medicine, Banat’s University of Agricultural Sciences and Veterinary Medicine „King Michael I of Romania” from Timisoara - USAMVB, 119 Calea Aradului, 300645, Timisoara, Romania 2Faculty of Bioengineering of Animal Production, Banat’s University of Agricultural Sciences and Veterinary Medicine „King Michael I of Romania from Timisoara -USAMVB, 119 Calea Aradului, 300645, Timisoara, Romania 3Faculty of Engineering of Hunedoara, Polytechnic University of Timisoara. The excess iron administered over a short period of time to rabbits influences the metabolism of several minerals such as potassium, magnesium, calcium, iron as well as sodium and chlorine and that is reflected in their blood serum level. The iron of hemeprotein plays a crucial role in binding of oxygen (hemoglobin and myoglobin carry oxygen), nitric oxide, carbon monoxide or hydrogen sulfide, processes that modulate signal transduction. All these indicate that iron is an essential mineral for living organisms, but it should only be present in certain amounts. In the present paper we evaluate the effect of iron overload for a short period of time in relation to serum potassium, magnesium, calcium, chlorine, and sodium levels
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