Abstract
Ionic currents in the plasmalemma of perfused Nitella syncarpa cells identified as currents through Ca 2+ channels were registered for the first time. The effect of 1,4-dihydropyridine derivatives (nifedipine, nitredipine, riodipine) and phenylalkylamines (verapamil, D600) as well as the agonist CGP-28392 on the Ca 2+ channels in the plasmelemma of perfused cells of Nitellopsis obtusa and Nitella syncarpa have been studied. A blocking effect of 1,4-dihydropyridine derivatives and phenylalkylamines on the plasmalemma Ca 2+ channels has been detected. Phenylalkylamines have been found to block both inward and outward Ca 2+ currents. The activating effect of the agonist CGP-28392 on the Ca 2+ channels of plasmalemma has been shown.
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