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https://doi.org/10.1055/s-2001-14587
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Cite Journal: Synlett |  Publication Date: Jan 1, 2001 |
 Citations: 161 |
Affiliation: GTx (United States), Indian Institute of Chemical Technology
An efficient synthesis of 3,4-dihydropyrimidines using bismuth chloride as a catalyst from an aldehyde, β-keto ester and urea in acetonitrile is described. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of good yields (56-97%).
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