Abstract
AbstractThe present study focuses on the biogenic synthesis of selenium nanoparticles (Se NPs) usingPelargonium zonaleleaf extract under microwave irradiation. Response surface methodology was used to evaluate the effects of the synthesis parameters, namely amounts of the leaf extract (0.5–2.5 ml) and amounts of the 10 mmsodium selenite solutions (15–65 ml), at constant microwave heating (4 min), on the concentration and particle size of the fabricated Se NPs, optimize the synthesis conditions and verify the generated models and the procedures. The obtained results indicated that Se NPs with preferable attributes of mean particle size (50 nm), zeta potential (−24.6 mV), absorbance [34.6% absorbance units (a.u.)] and broad absorption peak (319 nm) were formed at the optimum synthesis conditions including amounts of 1.48 ml and 15 mlPelargoniumleaf extract and sodium selenite solution, respectively. The antibacterial activities of the synthesized Se NPs againstEscherichia coliandStaphylococcus aureusindicated that the created NPs had higher antibacterial activities toward the Gram-positive bacteria. Furthermore, the synthesized Se NPs indicated higher antifungal activities againstColletotrichum coccodesandPenicillium digitatum.
Highlights
Selenium as an essential trace element for the human body and animals is a non-metal element with low toxicity [1]
The present study focuses on the biogenic synthesis of selenium nanoparticles (Se NPs) using Pelargonium zonale leaf extract under microwave irradiation
Response surface methodology was used to evaluate the effects of the synthesis parameters, namely amounts of the leaf extract (0.5–2.5 ml) and amounts of the 10 mm sodium selenite solutions (15–65 ml), at constant microwave heating (4 min), on the concentration and particle size of the fabricated Se NPs, optimize the synthesis conditions and verify the generated models and the procedures
Summary
Selenium as an essential trace element for the human body and animals is a non-metal element with low toxicity [1]. Selenium nanoparticles (Se NPs) indicate higher antitumor activity as compared to its organic and inorganic components in the bulk form [5]. Like other metal and non-metal NPs, Se NPs have attracted more interest because of their excellent bioavailability, antioxidant activity, anticancer property, and lower toxicity [2, 7, 8]. Several studies revealed the mentioned beneficial properties of the redness synthesized of Se NPs and their higher adsorptive ability interaction with numerous functional groups (i.e. N-H, C-O, COO and C-N) in human and animal bodies [7]
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