Abstract
The COVID-19 pandemic demonstrated the susceptibility of the United States and the world to biological threats. These threats can be unintentional, such as the result of zoonotic spillover or laboratory accidents, or deliberate, such as the release of a pathogen intended to be used as a biological weapon (or, bioweapons). While unintentional outbreaks are difficult to prevent, much effort has been spent to prevent the spread and use of bioweapons in the modern era. However, advances in technology threaten to outpace efforts to control bioweapon proliferation. This article reviews the changing nature of bioweapons, the governance structures established to prevent their spread, and the advances in technology that could deter and mitigate their use.
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