Abstract
The York Tissue Bank was established in 2013 at the University of York as a repository for cells and tissues to facilitate clinical and translational research at the university and with collaborative external tissue bank applicants. The bioresource described in this publication was initially established to conduct investigations into infection processes of sexually transmitted diseases in ex vivo organotypical models, specifically in uterine cervical tissue. Healthy human uterine cervical tissue is currently available to suitable applicants for ethically approved scientific research meeting the access criteria of the York tissue bank management committee. Funding statement: Funding to support the bioresource is from University of York.
Highlights
(1) Bioresource Overview Project description York Tissue Bank (YTB) is hosted within the Centre for Immunology and Infection in the Department of Biology and Hull York Medical School of the University of York and is approved by the Health Research Authority (National Research Ethics Service) Leeds East Research Ethics Committee; our license number granted by the Human Tissue Authority under section 16 (2) (e) (ii) of the Human Tissue act 2004 is 12604
Tissue was initially collected to meet the requirements of this study but latterly, following amendment to the ethically approved protocol and re-consent of patients, where possible, for the tissue bank and available for suitable tissue bank applicants to access
(2) Methods Steps Written informed consent using York Tissue Bank patient information sheets and consent forms was obtained from women willing to donate uterine cervical tissue who had normal cervical smears and were undergoing a planned hysterectomy for their own health
Summary
UK National Research Ethics Service (NRES 11/YH/0321) and Research & Development at York Teaching Hospital NHS foundation Trust (YORA01992) ethically approved a study entitled ‘ex vivo cervical implant systems for the analysis of viral infections and transmission blockade’ with the University of York as sponsor. (2) Methods Steps Written informed consent using York Tissue Bank patient information sheets and consent forms was obtained from women willing to donate uterine cervical tissue who had normal cervical smears and were undergoing a planned hysterectomy for their own health.
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