Abstract

Polymers are the key material in design of drug delivery systems. These have been shown as the spine for drug development process. These accept an essential part in rising of novel drug delivery systems to crush different intricacies in drug delivery. These are used for controlling the appearance of the drug in needed manner. The hydrophilic and lipophilic polymers are the most ideal choice for getting the ideal conveyance in controlled, manner at the target sites. Isolated of this, these fabricated and semisynthetic polymers are made by different chemical reactions and purification measures. Since these are prepared by different unit operations which are costly. By and by days different investigates are being examined for avoiding the characteristic, physiological and reasonable issues related with the synthetic and semisynthetic polymers. So an alternative rather than synthetic and semisynthetic polymers are being investigated having interest, probability, and any leftover benefits with least troublesome ramifications for environment and physiology of the people. One of the alternatives as opposed to designed and semisynthetic polymers is biopolymers which have pulled in the thought of researchers by using an economical procedures. Biopolymers are novel, adroit and sharp polymers which have been confined from various basic sources. Biopolymers isolated from natural sources might be utilized as novel excipients having a polymeric nature. These isolated biopolymers have superb bioretardant, bio stabilizer, and mucoadhesive properties. These have the brilliant film-framing capacity and biocompatibility properties. The isolated bio-polymers have great drug release rate controlling capacities. Since these are biodegradable and might be utilized as an option in contrast to standard manufactured synthetic and semisynthetic polymers. The isolated biopolymer shows critical biodegradable, mucoadhesive, filmability, and retardability properties which are like properties of standard polymers, may be the alternative in design of novel drug delivery system design.

Highlights

  • Biocomposites are natural fiber-reinforced biopolymers. Researchers are developing these materials as an alternative to standard materials which will be nonrenewable, recalcitrant, or manufactured by pollution emitting processes

  • The amorphous drug-loaded nanoparticles can be characterized in the nanosuspension as well as bionanosuspension. This can be evaluated by x-ray powder extraction, scanning electron microscopy (SEM) characterization, transmission electron microscopy (TEM) characterization

  • The excess of the isolated biomaterial was added in 10 ml of the specific solvent system in the beaker gradually

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Summary

Introduction

Researchers are developing these materials as an alternative to standard materials which will be nonrenewable, recalcitrant, or manufactured by pollution emitting processes. Biocomposites consist of a large variety of organic and inorganic compounds such as natural polymers, synthetic polymers, polysaccharides, sugars proteins, metals, and nanocarbon. While industrial-scale production of biocomposites is becoming. Biocomposites more viable, the sturdiness of those natural materials limits application in many environments. Biocomposites have been described as sustainable materials because of their biodegradability, low ecotoxicity

Biopolymers
Bionanoparticles as novel nanoparticulate system
Novel sonication method for nanoparticles preparation
Evaluation parameters for biopolymeric nanoformulation
Advantages of biopolymeric bionanoformulations over other formulations
Limitations of bionanoformulations
Researches on biopolymer
Bionanoformulation in drug targeting
Isolation and characterization of biopolymers
Isolation of biomaterial from the natural source
Physicochemical characterization
Solubility
Particle size analysis
Bulk density
Tapped density
Angle of repose
Tests for carbohydrate
Test for protein
Spectral analysis of the biomaterial
FTIR spectroscopy
Mass spectroscopy
Differential scanning calorimetry
Cytotoxicity evaluation of biomaterial
6.11 Preparation of drug dilutions: (serial dilution method)
Formulation of drug loaded bio-nanoparticulate system
Future aspects
Full Text
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