Abstract

Mitochondria are dynamic organelles that must precisely control their protein composition according to cellular energy demand. One way in which gene expression can be modulated post-transcriptionally is through localization of nuclear-encoded mRNAs to the mitochondrial surface. As yeast switch to respiratory metabolism, there is an increase in the fraction of the cytoplasm that is mitochondrial. Our data point to this change in mitochondrial volume fraction increasing the localization of certain nuclear-encoded mRNAs to the surface of the mitochondria.

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