Abstract

BIOMODULATORY POTENTIAL OF LOW-LEVEL LASER ON NEOANGIOGENESIS AND REMODELING TISSUE. A LITERATURE REVIEW

Highlights

  • Tissue repair process is a physiological response to injury, which usually results in total or partial restoration of tissue morphology and function

  • The increased number of new blood vessels accelerates the development of inflammation, neoangiogenesis and promotes tissue remodeling

  • The non-occurrence of this important biological phenomenon will result in delayed wound healing and/or deficient biosynthesis of the elements that integrate the new extracellular matrix[2,3]

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Summary

Literature review

How to cite this article: Fortuna T, Gonzalez AC, Ferreira MS, Reis S, Medrado A. Biomodulatory potential of low-level laser on neoangiogenesis and remodeling tissue. Neoangiogenesis is still an important process of tissue repair, since it always precedes collagen synthesis and matrix extracellular remodeling. Increasing scientific evidence has shown that photobiomodulation stimulates neoangiogenesis, fibroblast proliferation and collagen biosynthesis. Objective: Review the literature about the effects of low level laser therapy on neoangiogenesis and fibroplasia and describe how these processes occur in the tissue subjected to an injury. Methods and Matereials: The search tool used was the Medline / Pubmed and the following keywords were used: remodeling, wound healing, neoangiogenesis, fibroplasia, laser therapy, low-level laser. Results: Increasing scientific evidence has shown that photobiomodulation stimulates neoangiogenesis, fibroblast proliferation and collagen biosynthesis. Submitted 01/19/2018 , Accepted 02/20/2018, Published 02/23/2018 J Dent Pub H, Salvador, 2018 March;9(1):[95-103]

Introduction
Laser therapy and tissue repair
Variables of LLLT and its action in the repair
Laser action on angiogenesis
Neoangiogenesis and remodeling under laser action
Clinical use of LLLT
Findings
Final considerations

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