Abstract
Background: Noninvasive methods of treating initial caries lesions have been a widely researched topic in this scientific era. Various biomimetic materials are available on the market. Self-assembling peptides focus on the biomimetic regeneration of enamel and stand out from the others due to their ability to restore the enamel matrix Data: This systematized review was conducted on articles with the remineralization effects of SAP on initial enamel lesions published between 2019 January to 2024 September. Sources: The search of this review was carried out in the electronic databases PUBMED, COCHRANE, EMBASE, and Google Scholar. Only primary researches were included Results: Out of 122 articles obtained, 28 articles were included in this review after screening. The studies demonstrate the effect of SAP on reversing WSLs and its efficacy in comparing and combining with other remineralizing agents such as fluorides, and CPP-ACP. Conclusion: With the limited evidence, SAP can be used as a promising solution for WSLs in permanent as well as primary teeth
Published Version
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