Abstract
AbstractMagnetic nanoparticles (MNPs) have been identified as promising tools with potential use in a wide range of areas, spreading from diagnostics to the treatment of diseases. The high magnetization value and ability to pass cellular barriers promote them to be used as magnetic resonance imaging (MRI) agents, gene delivery agents, hyperthermia therapy, and for tissue repair. Use of functionalized MNPs with macromolecules minimizes their risks in biological systems and offers organ specific diagnosis and therapy. MNPs functionalized with dendrimers can have better potential in terms of enhanced stability and dispersibility in aqueous solution. The particular review summarizes the recent advances in synthesis of dendrimer functionalized MNPs and their applications in biomedical field such as targeted drug delivery, MRI, magnetic hyperthermia treatment and as antimicrobial agent.
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