Abstract
OSTEOTRANS MX® (Takiron Co., Ltd., Osaka, Japan) is a bioactive resorbable maxillofacial osteosynthetic material composed of an unsintered hydroxyapatite/poly-l-lactide composite, and its effective osteoconductive capacity has been previously documented. However, the mechanical strength of this plate system is unclear. Thus, the aim of this in vitro study was to assess its tensile and shear strength and evaluate the biomechanical intensity of different osteosynthesis plate designs after sagittal split ramus osteotomy by simulating masticatory forces in a clinical setting. For tensile and shear strength analyses, three mechanical strength measurement samples were prepared by fixing unsintered hydroxyapatite/poly-l-lactide composed plates to polycarbonate skeletal models. Regarding biomechanical loading evaluation, 12 mandibular replicas were used and divided into four groups for sagittal split ramus osteotomy fixation. Each sample was secured in a jig and subjected to vertical load on the first molar teeth. Regarding shear strength, the novel-shaped unsintered hydroxyapatite/poly-l-lactide plate had significantly high intensity. Upon biomechanical loading evaluation, this plate system also displayed significantly high stability in addition to bioactivity, with no observed plate fracture. Thus, we have clearly demonstrated the efficacy of this plate system using an in vitro model of bilateral sagittal split ramus osteotomy of the mandible.
Highlights
The standard osteofixation in orthognathic surgery has been titanium osteosynthesis for many years [1,2]
OSTEOTRANS MX® (Takiron Co., Ltd., Osaka, Japan), called Super FIXSORB MX® in Japan, is a bioactive and totally resorbable maxillofacial osteosynthetic bone fixation material, which has been reported to exhibit clinical efficacy with relatively long-term results [5,6]. Both the strength and stability of this plate system are still unclear. The aims of this in vitro study were to assess the physical strength of this bioactive resorbable plate system, as well as the biomechanical intensity of different osteosynthesis plate designs after sagittal split ramus osteotomy (SSRO) by simulating masticatory forces in a clinical setting
Forged composites of unsintered hydroxyapatite/poly-L -lactide (u-HA/PLLA), prepared via the same means as OSTEOTRANS MX®, were processed by machining or milling treatments into various miniscrews and miniplates, which, respectively, contained 30 and 40 weight fractions of u-HA particles in composites
Summary
The standard osteofixation in orthognathic surgery has been titanium osteosynthesis for many years [1,2]. OSTEOTRANS MX® (Takiron Co., Ltd., Osaka, Japan), called Super FIXSORB MX® in Japan, is a bioactive and totally resorbable maxillofacial osteosynthetic bone fixation material, which has been reported to exhibit clinical efficacy with relatively long-term results [5,6]. Both the strength and stability of this plate system are still unclear. The aims of this in vitro study were to assess the physical strength of this bioactive resorbable plate system, as well as the biomechanical intensity of different osteosynthesis plate designs after sagittal split ramus osteotomy (SSRO) by simulating masticatory forces in a clinical setting
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