Biologically Active Glycosides from Asteroidea, 36. Re‐examination of the Structure of Acanthaganglioside C, and the Identification of Three Minor Acanthagangliosides F, G and H

Abstract

AbstractThe structure of acanthaganglioside C (1) has been re‐examined using MQ‐COSY, TOCSY, NOESY, HSQC, HMBC and HSQC‐TOCSY experiments. As a result, it is clarified that N‐acetyl neuraminic acid (NeuAc) is linked to the C‐3 position, and not the C‐4 position, of the β‐galactopyranose. In addition, three minor acanthagangliosides, F (2), G (3) and H (4), have also been isolated from the ganglioside molecular species AG‐2. Their structures have been determined on the basis of chemical and spectroscopic evidence.