Biological activity and its related compounds of Red Jasmine rice extracts linked to normal fibroblast viability for cosmetic product

Pahol Sansomchai,Wilart Pompimon,Pongsatorn Khamjainuk,Tiparat Tikapunya

doi:10.5267/j.ccl.2021.9.004

Abstract

Red jasmine rice is recognized as a healthy food with high phenolic compounds. These compounds present antibacterial and anti-free radical properties. Moreover, colored rice exhibits a biological activity against anticancer. Objectives of this study are 1) exploring a biological screening and cell viability of 70% ethanol and aqueous extracts of red jasmine rice, 2) investigating cytotoxicity to fibroblast NIH3T3 (IC80) that is one hundred cells were found cell viability 80 cells. Red jasmine rice extracts were dried and transformed into a powder using the freeze-drying method. The extracts were treated with fibroblast NIH3T3 for MTT. The highest of IC50 of red jasmine rice extract to scavenge the DPPH and ABTS radicals was found in ethanol extract (53.20±7.37 and 64.17±5.76, respectively). The experiment showed that the ethanol and aqueous extract of red rice did not show cytotoxicity to fibroblast NIH3T3 (IC80). The extracts of red rice show the biological screening of anti-oxidation with total phenolic compounds and flavonoid contents. Moreover, it does not modify the physical properties of the cream formula. It can be concluded that the red rice extract is highly promising for the value addition.

Highlights

Red jasmine rice is well-known and has grown in Thailand for more than 10 years
Red jasmine rice crude extracts against ABTS and DPPH radicals and their total phenolic (TP) and total flavonoid (TF) contents
The anthocyanin contents were found in red jasmine rice extract in water extract (W) and ethanol extract (EtOH)

Summary

Introduction

Red jasmine rice is well-known and has grown in Thailand for more than 10 years. One of the major characteristics of this cultivar is having a high anti-oxidant compound[1]. Other properties of red rice such as anticancer[2], antimicrobial activity[3], and reduced glucose response in healthy people[4] were studied. Thai rice has more varieties reported for biological effect in various aspects, especially in colored rice provided by phenolic acid, flavonoids, and anthocyanins (Cyanidin 3-glucoside, peonidin 3-glucoside, cyanidin chloride)[6]. Colored rice can modulate skin for anti-aging with its Oryzanol and phenolic compounds such as a proanthocyanidin[7, 8] and anthocyanin[9]. The proanthocyanidin from colored rice affects the skin anti-aging via improving a matrix metalloprotenase 2 (MMP2) degradation to collagenase degradation[10,11] and inhibit mitogen-activated protein kinases (MAPK) induced UVB-irradiation[12]. Another phenolic compound with anti-aging properties in colored rice is anthocyanin[9]

Objectives

Results

Conclusion