Bioinformation Algorithm for Selecting a Method for Premedication of Patients with Arterial Hypertension with Amiodarone-Associated Thyrotoxicosis Type I during Neurosurgical Operations

Abstract

Signs associated with adverse cardiovascular reactions after surgery were established in 46 patients with arterial hypertension, cardiac arrhythmias and type I amiodarone-associated thyrotoxicosis. These signs included an increase in the circadian index above 1.52, the presence of pauses in the heart rate for more than 3 seconds, the number of group ventricular extrasystoles per day exceeding 30, an increase in LF/HF with RR-intervalometry more than 1.3. In order to reduce the risk of cardiac arrhythmias in the postoperative period, a premedication with long-acting benzodiazepines in combination with magnesium preparations over a prolonged course is recommended.