Pharmacological optimization of premedication to reduce the risk of cardiovascular complications

А В Сафроненко ,Yu S Maklyakov,S V Lepyavka,И А Демидов ,А А Демидова ,Irina Vladimirovna Dubatova

doi:10.33647/2713-0428-17-3e-183-191

А В Сафроненко , Yu S Maklyakov + Show 4 more

Open Access

https://doi.org/10.33647/2713-0428-17-3e-183-191

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Journal: Journal Biomed	Publication Date: Oct 26, 2021
License type: cc-by

Affiliation: Rostov State Medical University

Abstract

In 46 patients with arterial hypertension, arrhythmias and amiodarone-associated type I thyrotoxicosis, it was confirmed that prolonged premedication with long-acting benzodiazepines and magnesium preparations reduces the risk of cardiovascular complications and instability of systemic hemodynamics, mitigates the adverse effects of amiodarone dysfunction of the thyroid gland on the cardiovascular system. Postoperatively, under prolonged premedication with long-acting benzodiazepines and magnesium preparations, postoperative cardiac arrhythmias were found to be less common. When the pre-operative period was significantly reduced, the appointment of long-acting benzodiazepines had advantages over short-acting benzadiazepines due to the prevention of cardiac arrhythmias and increased blood pressure in the early post-operative period.

Highlights

Rostov State Medical University of the Ministry of Health Сare of Russia 344022, Russian Federation, Rostov-on-Don, Nakhichevanskiy Lane, 29
При суточном мониторировании ЭКГ после операции частота суправентрикулярных экстрасистол была у меньшего числа больных 1-й подгруппы (37,5%) и чаще встречалась во 2-й (60%) и 3-й (80%) подгруппах
In 46 patients with arterial hypertension, arrhythmias and amiodarone-associated type I thyrotoxicosis, it was confirmed that prolonged premedication with long-acting benzodiazepines and magnesium preparations reduces the risk of cardiovascular complications and instability of systemic hemodynamics, mitigates the adverse effects of amiodarone dysfunction of the thyroid gland on the cardiovascular system

Summary

Introduction

Rostov State Medical University of the Ministry of Health Сare of Russia 344022, Russian Federation, Rostov-on-Don, Nakhichevanskiy Lane, 29. При суточном мониторировании ЭКГ после операции частота суправентрикулярных экстрасистол была у меньшего числа больных 1-й подгруппы (37,5%) и чаще встречалась во 2-й (60%) и 3-й (80%) подгруппах. Пробежек желудочковой тахикардии в подгруппах пациентов до и после операции не различалась.

Results

Conclusion