Abstract
Most bacteria in nature do not exist as free-floating isolated cells; instead, they usually have to do with surfaces. These microbial communities, or biofilms, are made of bacteria that are encased in self-generated Extracellular Polymeric Substances (EPS). Biofilms can exhibit extreme integrity and resistance to environmental pressures. This is mainly because of factors including their physiological condition, cell density, the presence of quorum sensing, the significant role of drug efflux pumps, mutations and overexpression of genes, and the persistent cells. From the mitigation effect of biofilms to the application of beneficial biofilms, the unique characteristics of biofilms have triggered a lot of discussion and research. In this paper, we combine various reading materials to discuss how the structure and properties of biofilms confer the ability to be utilized. Then, with reference to the research paper of Manisha Mukherjee et al., the prospect of inhibiting biofilm formation by engineering quorum quenching biofilm was discussed.
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