Abstract
The biofilm inhibitory effects of Lactobacillus spp against Streptomycin-resistant uropathogenic Escherichia coli (UPEC) were evaluated using the crystal violet test method. Lactobacillus spp were isolated from milk samples while fifty strains of Uropathogenic Escherichia coli were isolated from urine samples from Urinary Tract Infection patients attending Federal Medical Centre (FMC) Owerri, Nigeria. Ten of the E. coli strains resistant to streptomycin antibiotics were screened for their susceptibility to antibiofilm effect of Lactobacillus secondary metabolites extracts. From the result obtained, only one of the E. coli strains was susceptible while nine strains were resistant. This result shows clearly that the metabolite extracts from Lactobacillus sp were not effective in the antibiofilm activity of the E. coli strains and thus not a good candidate for the management of UTI caused by E. coli.
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