Abstract
Bioelectronic devices enable fundamental physiological and electrophysiological research, healthcare monitoring, and advanced therapeutics. To meet the demanding device requirements imposed by biomedical applications, graphene-based electronics offer a promising alternative to conventional bioelectronic device materials in an all-carbon platform. Continued advancements in graphene nanostructure synthesis and micro-fabrication techniques allow novel device architectures with vastly tunable physiochemical properties. Here, we highlight recent advances in graphene nanostructure-based bioelectronics. We distinguish between various material geometries and discuss their effect on device performance. Furthermore, we emphasize the continued development of fundamental relationships between 3D device geometries and material properties to allow next-generation bioelectronics for biosensing, electrophysiological recordings, and stimulation.
Highlights
Bioelectronic devices enable real-time monitoring or control of physiological processes.[1]
In the case of bioelectronic devices interfaced with electrogenic cells, the electrophysiology recording and stimulation capabilities of the devices are dependent on the impedance of the electrode,[8,14] the exposed surface area,[15] and the cell-electrode coupling.[14]
The topography of the bioelectronic interface and the dimensionality of the constituent materials play a dominant role in the overall device performance
Summary
Bioelectronic devices enable real-time monitoring or control of physiological processes.[1].
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