Abstract
Biodegradable macromolecule based topical gels containing natural oils in the management of burn wounds
Highlights
Topical preparations like gels and hydrogels are among the most frequently used dressing materials in the treatment of wounds and burns
The standardization of black cumin oil, chicken skin oil and flax seed oil carried out as per standard procedures showed that the experimentally obtained values for various physicochemical parameters were within the range as specified in standard texts confirming the purity of the oils (Table 1)
The Gas Chromatography- Mass Spectrometric (GC-MS) analysis of standard oleic acid ester showed a sharp peak eluting at 21.880 min. with m/e 296 characteristic of oleic acid (Figure 1)
Summary
Topical preparations like gels and hydrogels are among the most frequently used dressing materials in the treatment of wounds and burns. These systems are capable of maintaining moisture at the site of application, allow oxygen penetration and are capable of absorbing water from wound mass. In the last decade has received tremendous attention in biomedical and pharmaceutical applications. Their utility in wound healing, hemostasis, immune enhancement with anti-microbial properties, makes it an excellent polymer for use in wound healing and skin tissue regeneration. Dai T. et al has reported in an extensive review the use of chitosan preparations for treatment of wounds and burns, both by virtue of its intrinsic antimicrobial properties and its ability to deliver extrinsic antimicrobial agents to wounds and burns [6]
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