Abstract
Connective tissue response and push-out bond strengths of a new (mineral trioxide aggregate) MTA based endodontic sealer were evaluated.Polyethylene tubes containing ProRoot ES and Endosequence BC sealers were subcutaneously implanted in 45 rats. After 3, 7, 30 days the animals were euthanized, and the specimens were evaluated histologically. Bond strengths of the sealers to root dentine were measured using a push-out bond strength test.Scores of the inflammatory tissue reaction for ProRoot® ES were significantly lower than BC sealer group at 3 days with a thinner fibrous capsule at 30 days. Also, they were not significantly different from the control group. The push-out bond strength of ProRoot® ES could not be evaluated due to handling problems, nevertheless the measured Endosequence BC bond strengths were within an acceptable range.ProRoot® ES had better biocompatibility, seen as more favorable tissue response, than the BC Sealer, although the latter had improved handling characteristics.
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