Abstract
1. 1. Female Gambusia affinis have a greater capacity for O-dealkylation of p-nitrophenyl ethers and DDT analogues and the formation of acid-labile conjugates than to mosquito larvae, fat-head minnows, or two species of pulmonate snails. 2. 2. The p-nitrophenyl ethers are O-de-ethylated most readily by all species, while the DDT analogues are O-demethylated most readily. 3. 3. Fish absorb the greatest amount of insecticide in a 24-hour period; the excretion rate is highest in Gambusia and lowest in the minnow. 4. 4. The toxicity of DDT analogues correlates with metabolism data, except in snails, which are naturally tolerant to chlorinated hydrocarbons.
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