Abstract
Bispyribac-sodium (nominee (used extensively as a herbicide in rice fields in Egypt. We investigate the cytotoxic effect of bispyribac-sodium in albino rats that intubated orally with 0, 16.47, 32.94, 65.88 mg/kg of bispyribac-sodium (equivalent to 1/160 1/80 and 1/40 of the LD50 of bispyribac-sodium) for three months twice per week. It was found that bispyribac-herbicide caused non-significant decrease in the body weight gain ratio of albino rats. Moreover, bispyribac-sodium elevated significance levels of ALT, AST, urea, creatinine and LDH. In contrast, bispyribac herbicide decreased significant levels of glucose, cholesterol, total protein and albumin. Bispyribac-sodium showed histopathological changes in liver, lungs, kidney and spleen, but had no significant effect on RBCs count while showing significant increases in leukocyte count. On the conclusions, bispyribac sodium had a toxic effect on liver, lungs and kidney of female albino rats.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
