Biochemical diagnosis of aortic dissection by raised concentrations of creatine kinase BB-isozyme

Abstract

Listen

Translate article

Aortic dissection is associated with a high mortality and morbidity. Despite advancements in surgical and medical treatment, aortic dissection is often diagnosed too late or is overlooked. There have been improvements in diagnostic imaging, such as transesophageal echocardiography and magnetic resonance imaging, but biochemical diagnosis have not been explored. We have reported raised serum smooth-muscle-myosin heavy chain concentrations in aortic dissection;1–3 we now show creatine kinase BB-isozyme concentrations to be raised in acute aortic dissection.