Abstract
ABSTRACT This sequential treatment trial compared the bioavailability of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from salmon patties fortified with fish oil (DHA:EPA ratio = 1.8, total DHA + EPA about 2.2 g), unfortified salmon patties (DHA:EPA ratio = 1.9, total DHA + EPA about 1.1 g), and fish oil capsules (DHA:EPA ratio = 1.6, total DHA + EPA = 500 mg) in healthy older adults. Fortified salmon patties produced a significantly higher mean incremental area under the curve (AUCfasting‐9 h) than unfortified patties for plasma EPA (37.6 in contrast to 12.9 μg·h/mL, p= 0.017), for plasma DHA (103.7 in contrast to 40.8 μg·h/mL, p= 0.035) and for plasma EPA + DHA (141.2 in contrast to 53.7 μg·h/mL, p= 0.031). Plasma EPA and DHA responses were larger with the fortified than the unfortified patties, indicating that fish oil incorporated into the salmon patties was bioavailable.
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