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Abstract
Studies on extended beta lactamase producing, biofilm forming clinical bacterial pathogens and its invitro inhibition by Actinobacterial extractsHemachandran. K., S. Bharathi, M. Radhakrishnan, R. Balagurunathan
Highlights
The discovery of antibiotics to treat infectious diseases has revolutionized the field of medicine in the mid-twentieth century
The present study reports the bioactive potential of actinobacteria isolated from certain under-studied regions in India
Bioactive compound from all the isolates were produced by agar surface fermentation and its activity was tested by agar plug method against S. aureus, E. coli and C. albicans
Summary
The discovery of antibiotics to treat infectious diseases has revolutionized the field of medicine in the mid-twentieth century. Due to overuse or misuse of antibiotics over a prolonged period, most of the pathogens have become resistant to the antibiotic therapy. There is a dire need for the discovery and development of new antibiotics to effectively target the life threatening disease causing pathogens (Sharma et al, 2016). Actinobacteria are of great importance in terms of secondary metabolite producers with promising biological activities. They produce two-thirds of all naturally derived antibiotics in current clinical use as well as many anticancer, antifungal and antiviral compounds (Barka et al, 2016)
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