Abstract
Today urinary tract infection causing Escherichia coli is also serious problem among pregnant women especially during pandemic period. So the mid stream urine samples were collected from different clinics and Public Health Centre in from rural area of Salem city. Totally 25 E. coli was isolated from 25 mid stream urine samples and confirmed by biochemical test and growth parameters. In this study the optimum growth was recorded in pH 7 at 37ᵒC. To date the patterns of resistance to the antimicrobial agents may be due to indiscriminate, wide spread and lengthy use of antibiotics in the treatment of UTI particularly in pandemic situation 2022. So, the present research targeted to extract the therapeutic drug from the high medicinal value of ethano medicinal plant extract because it having anti-UTI compound to diagnose the UTI infection. In this research the antibacterial activity of Terminalia chebula, Allium sativum, Laurus nobilis, Hybamthus enneapermus, Cinnamomum tamala and Zingiber officinale was studied by agar well diffusion method. Four different concentrations (25μl, 50μl, 75μl and 100μl) were used against Escherichia coli. The maximum zone of inhibition were observed in plant extracts Terminalia chebula 11mm, 13mm, 16mm and 20mm in strain no. EC05 followed by minimum zone of inhibition was observed in the plant extract Hybamthus enneapermus 10mm in strain no. EC05 at 100μl concentration of crude plant extracts. The research proved the ethano medicinal plant extract to cleave the pathogenic cell wall of E. coli.
 Keywords: E. coli, Urinary tract infection, Pregnancy Women, Medicinal Plant Extracts
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