Abstract

SODIUM alginates markedly inhibit the intestinal absorption of strontium in rats1–4 and man5,6 without an appreciable effect on calcium absorption so that they are of interest as possible therapeutic agents in cases of ingestion of strontium-90. Alginic acid is obtained from certain seaweeds and is a polymer of D-mannuronic acid and L-guluronic acid7 joined by 1,4 linkages8. It has been shown that guluronic-rich fractions of alginate are the most effective in reducing strontium absorption in rats in vivo and in vitro4,9.

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