Abstract
IT has been established that intestinal absorption of strontium is inhibited by sodium alginate taken orally, both in the rat1–3 and in man4,5, while calcium absorption is not significantly reduced. Alginic acid is a polyuronide composed of L-guluronic and D-mannuronic acid residues6; both acids can occur in the same uronide chain7. Polygalacturonic acid was also found to inhibit the absorption of strontium more than that of calcium, when given to rats by stomach tube8. The effect of polyuronides other than alginate and polygalacturonate on the intestinal absorption of strontium has not been ascertained.
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