Abstract
A 62-year-old man with long-standing chronic lymphocytic leukemia (CLL) and hypoglobulinemia presented at our institution for evaluation of intractable diarrhea for 6 months. His diarrhea was complicated by dehydration requiring repeated hospitalizations, malnutrition with 30-pound weight loss, and anorexia. He was receiving total parenteral nutrition for maintenance of hydration. On previous evaluation, his diarrhea was attributed to cryptosporidiosis, diagnosed by a small-bowel biopsy, which had been refractory to treatments with azithromycin, paromomycin, and nitazoxanide.
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