Abstract
Oral precancerous lesions are potentially malignant disorders, consisting of a group of diseases, which should be diagnosed in the early stage. Oral leukoplakia, oral submucous fibrosis, oral erythroplakia and lichen planus are the most common oral mucosal diseases that have a very high malignant transformation rate. There are various etiological factors amongst which consumption of tobacco or alcohol, chewing betel nut are the predominant factors. Early diagnosis is very important and can be lifesaving, because in late stages, they may be progressed to severe dysplasia and even carcinoma in situ and/or squamous cell carcinoma. The following case report highlights the treatment outcome using retinoids and antioxidants in treating erythroplakia and leukoplakia in a 55 year old male patient. Key Words: Leukoplakia, erythroplakia, pre-cancerous lesions, pre-malignant lesions, malignant transformation
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