Bilateral ovarian carcinoma with colorectal metastases - An unusual presentation

Abstract

Primary ovarian carcinoma may metastasize to the peritoneum leading to malignant ascites. Four percent cases of primary ovarian carcinoma can involve the colorectum. We present a case report of a 50-year-old women who had complaints of bilateral adnexal mass and disturbed menstruation with altered bowel habits. Computed tomography scan of the abdomen and pelvis showed a bilaterally enlarged ovaries and a lobular rectal mass. Proctoscopy substantiated the rectal mass as an ulcerated lesion. Histopathology confirmed the diagnosis as bilateral serous papillary cystadenocarcinoma. Left hemicolectomy specimen illustrated foci of atypical glands. Immunohistochemical staining of both the tumor masses showed strong cytokeratin 7 positivity with negative cytokeratin 20 expression. Bilateral involvement of the ovaries with colorectal metastasis is very uncommon, which is highlighted in this paper. Keywords: Bilateral, Cancer, Colorectum, Immunohistochemistry, Ovary, Metastasis.