Abstract

We report a case of a child with nephrotic syndrome (NS), who presented an acute convergent strabismus, double vision and papilledema one week after a history of badly treated sinusitis. The image study revealed an extensive thrombosis of the intracranial sinuses that was treated with intravenous heparin and oral corticosteroids. Four months later, the case evolved with spontaneous resolution of the ocular deviation and no diplopia.

Highlights

  • The abducent nerve is the most affected cranial pair in cases of acquired paralytic strabismus[1]

  • Bilateral involvement is more common in children, and one important etiology to be considered is the increase of intracranial pressure, which can be idiopathic or secondary to many disorders, such as neoplasia, cerebral venous thrombosis, drugs, endocrine abnormalities and infectious causes[2]

  • In patients with nephrotic syndrome (NS), cerebral venous sinus thrombosis is a rare complication, with a few cases described in the literature

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Summary

Introduction

The abducent nerve is the most affected cranial pair in cases of acquired paralytic strabismus[1]. Bilateral involvement is more common in children, and one important etiology to be considered is the increase of intracranial pressure, which can be idiopathic or secondary to many disorders, such as neoplasia, cerebral venous thrombosis, drugs, endocrine abnormalities and infectious causes[2]. In patients with NS, cerebral venous sinus thrombosis is a rare complication, with a few cases described in the literature. This probably represents an underestimated incidence, once many cases are asymptomatic or not diagnosed in time[3]. Spontaneous resolution of the case can occur in many patients

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